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Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability

Chromatography was born approximately one century ago and has undergone outstanding technological improvements in innovation, research, and development since then that has made it fundamental to advances in knowledge at different levels, with a relevant impact on the well-being and health of individ...

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Autores principales: Câmara, José S., Martins, Cátia, Pereira, Jorge A. M., Perestrelo, Rosa, Rocha, Sílvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412595/
https://www.ncbi.nlm.nih.gov/pubmed/36014506
http://dx.doi.org/10.3390/molecules27165267
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author Câmara, José S.
Martins, Cátia
Pereira, Jorge A. M.
Perestrelo, Rosa
Rocha, Sílvia M.
author_facet Câmara, José S.
Martins, Cátia
Pereira, Jorge A. M.
Perestrelo, Rosa
Rocha, Sílvia M.
author_sort Câmara, José S.
collection PubMed
description Chromatography was born approximately one century ago and has undergone outstanding technological improvements in innovation, research, and development since then that has made it fundamental to advances in knowledge at different levels, with a relevant impact on the well-being and health of individuals. Chromatography boosted a comprehensive and deeper understanding of the complexity and diversity of human–environment interactions and systems, how these interactions affect our life, and the several societal challenges we are currently facing, namely those related to the sustainability of our planet and the future generations. From the life sciences, which allowed us to identify endogenous metabolites relevant to disease mechanisms, to the OMICS field, nanotechnology, clinical and forensic analysis, drug discovery, environment, and “foodprint”, among others, the wide range of applications of today’s chromatographic techniques is impressive. This is fueled by a great variability of powerful chromatographic instruments currently available, with very high sensitivity, resolution, and identification capacity, that provide a strong basis for an analytical platform able to support the challenging demands of the postgenomic and post COVID-19 eras. Within this context, this review aims to address the great utility of chromatography in helping to cope with several societal-based challenges, such as the characterization of disease and/or physiological status, and the response to current agri-food industry challenges of food safety and sustainability, or the monitoring of environmental contamination. These are increasingly important challenges considering the climate changes, the tons of food waste produced every day, and the exponential growth of the human population. In this context, the principles governing the separation mechanisms in chromatography as well the different types and chromatographic techniques will be described. In addition, the major achievements and the most important technological advances will be also highlighted. Finally, a set of studies was selected in order to evince the importance of different chromatographic analyses to understand processes or create fundamental information in the response to current societal challenges.
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spelling pubmed-94125952022-08-27 Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability Câmara, José S. Martins, Cátia Pereira, Jorge A. M. Perestrelo, Rosa Rocha, Sílvia M. Molecules Review Chromatography was born approximately one century ago and has undergone outstanding technological improvements in innovation, research, and development since then that has made it fundamental to advances in knowledge at different levels, with a relevant impact on the well-being and health of individuals. Chromatography boosted a comprehensive and deeper understanding of the complexity and diversity of human–environment interactions and systems, how these interactions affect our life, and the several societal challenges we are currently facing, namely those related to the sustainability of our planet and the future generations. From the life sciences, which allowed us to identify endogenous metabolites relevant to disease mechanisms, to the OMICS field, nanotechnology, clinical and forensic analysis, drug discovery, environment, and “foodprint”, among others, the wide range of applications of today’s chromatographic techniques is impressive. This is fueled by a great variability of powerful chromatographic instruments currently available, with very high sensitivity, resolution, and identification capacity, that provide a strong basis for an analytical platform able to support the challenging demands of the postgenomic and post COVID-19 eras. Within this context, this review aims to address the great utility of chromatography in helping to cope with several societal-based challenges, such as the characterization of disease and/or physiological status, and the response to current agri-food industry challenges of food safety and sustainability, or the monitoring of environmental contamination. These are increasingly important challenges considering the climate changes, the tons of food waste produced every day, and the exponential growth of the human population. In this context, the principles governing the separation mechanisms in chromatography as well the different types and chromatographic techniques will be described. In addition, the major achievements and the most important technological advances will be also highlighted. Finally, a set of studies was selected in order to evince the importance of different chromatographic analyses to understand processes or create fundamental information in the response to current societal challenges. MDPI 2022-08-18 /pmc/articles/PMC9412595/ /pubmed/36014506 http://dx.doi.org/10.3390/molecules27165267 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Câmara, José S.
Martins, Cátia
Pereira, Jorge A. M.
Perestrelo, Rosa
Rocha, Sílvia M.
Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
title Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
title_full Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
title_fullStr Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
title_full_unstemmed Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
title_short Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
title_sort chromatographic-based platforms as new avenues for scientific progress and sustainability
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412595/
https://www.ncbi.nlm.nih.gov/pubmed/36014506
http://dx.doi.org/10.3390/molecules27165267
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