Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate

This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using Design-Expert(®) software. The independent vari...

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Detalles Bibliográficos
Autores principales: Zaki, Randa Mohammed, Alfadhel, Munerah M., Alossaimi, Manal A., Elsawaf, Lara Ayman, Devanathadesikan Seshadri, Vidya, Almurshedi, Alanood S., Yusif, Rehab Mohammad, Said, Mayada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412614/
https://www.ncbi.nlm.nih.gov/pubmed/36015089
http://dx.doi.org/10.3390/ph15080940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412614/
https://www.ncbi.nlm.nih.gov/pubmed/36015089
http://dx.doi.org/10.3390/ph15080940

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