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Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation

(1) Background: Supercritical CO(2) fluid (SCF-CO(2))-assisted impregnation presents advantages on loading active drugs to polymer substrates, since it enables the realization of a drug-loaded polymer without any solvent residue. Besides, CO(2) gas and drugs can be recycled and utilized again. Resve...

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Autores principales: Zhu, Weiwei, Long, Jiajie, Shi, Meiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412637/
https://www.ncbi.nlm.nih.gov/pubmed/36013689
http://dx.doi.org/10.3390/ma15165552
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author Zhu, Weiwei
Long, Jiajie
Shi, Meiwu
author_facet Zhu, Weiwei
Long, Jiajie
Shi, Meiwu
author_sort Zhu, Weiwei
collection PubMed
description (1) Background: Supercritical CO(2) fluid (SCF-CO(2))-assisted impregnation presents advantages on loading active drugs to polymer substrates, since it enables the realization of a drug-loaded polymer without any solvent residue. Besides, CO(2) gas and drugs can be recycled and utilized again. Resveratrol-loaded diacetate fiber by SCF-CO(2)-assisted impregnation was done to give diacetate fiber biological activity function for enhancing its added value. (2) Methods: The effect of SCF-CO(2) temperature, pressure and treatment time on loading ability (LA) of resveratrol onto diacetate fiber was explored by ultraviolet visible spectrophotometer. The variation of structure and property of diacetate fiber was analyzed by characterization instruments. (3) Results: LA had been increasing with SCF-CO(2) treatment time, temperature and pressure when SCF-CO(2) was above 70 °C, 12 MPa. The inhibiting rate of resveratrol to free radicals was affected positively by SCF-CO(2). After resveratrol was impregnated by SCF-CO(2) it appeared some small white granular substances on the surface of diacetate fiber. It had a good interaction between resveratrol and molecular chain of diacetate fiber. (4) Conclusions: Resveratrol was well-loaded onto the diacetate fiber by SCF-CO(2) assisted impregnation.
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spelling pubmed-94126372022-08-27 Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation Zhu, Weiwei Long, Jiajie Shi, Meiwu Materials (Basel) Article (1) Background: Supercritical CO(2) fluid (SCF-CO(2))-assisted impregnation presents advantages on loading active drugs to polymer substrates, since it enables the realization of a drug-loaded polymer without any solvent residue. Besides, CO(2) gas and drugs can be recycled and utilized again. Resveratrol-loaded diacetate fiber by SCF-CO(2)-assisted impregnation was done to give diacetate fiber biological activity function for enhancing its added value. (2) Methods: The effect of SCF-CO(2) temperature, pressure and treatment time on loading ability (LA) of resveratrol onto diacetate fiber was explored by ultraviolet visible spectrophotometer. The variation of structure and property of diacetate fiber was analyzed by characterization instruments. (3) Results: LA had been increasing with SCF-CO(2) treatment time, temperature and pressure when SCF-CO(2) was above 70 °C, 12 MPa. The inhibiting rate of resveratrol to free radicals was affected positively by SCF-CO(2). After resveratrol was impregnated by SCF-CO(2) it appeared some small white granular substances on the surface of diacetate fiber. It had a good interaction between resveratrol and molecular chain of diacetate fiber. (4) Conclusions: Resveratrol was well-loaded onto the diacetate fiber by SCF-CO(2) assisted impregnation. MDPI 2022-08-12 /pmc/articles/PMC9412637/ /pubmed/36013689 http://dx.doi.org/10.3390/ma15165552 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhu, Weiwei
Long, Jiajie
Shi, Meiwu
Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation
title Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation
title_full Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation
title_fullStr Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation
title_full_unstemmed Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation
title_short Resveratrol-Loaded Diacetate Fiber by Supercritical CO(2) Fluid Assisted Impregnation
title_sort resveratrol-loaded diacetate fiber by supercritical co(2) fluid assisted impregnation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412637/
https://www.ncbi.nlm.nih.gov/pubmed/36013689
http://dx.doi.org/10.3390/ma15165552
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AT longjiajie resveratrolloadeddiacetatefiberbysupercriticalco2fluidassistedimpregnation
AT shimeiwu resveratrolloadeddiacetatefiberbysupercriticalco2fluidassistedimpregnation