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Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score

Background and Objectives: The improved life expectancy was associated to the increased in the incidence of hip fractures among elderly people. Subjects suffering hip fractures frequently show concomitant conditions causing prolonged lengths of stay and higher in-hospital mortality. The knowledge of...

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Autores principales: Di Martino, Giuseppe, Di Giovanni, Pamela, Cedrone, Fabrizio, D’Addezio, Michela, Meo, Francesca, Scampoli, Piera, Romano, Ferdinando, Staniscia, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412693/
https://www.ncbi.nlm.nih.gov/pubmed/36013549
http://dx.doi.org/10.3390/medicina58081082
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author Di Martino, Giuseppe
Di Giovanni, Pamela
Cedrone, Fabrizio
D’Addezio, Michela
Meo, Francesca
Scampoli, Piera
Romano, Ferdinando
Staniscia, Tommaso
author_facet Di Martino, Giuseppe
Di Giovanni, Pamela
Cedrone, Fabrizio
D’Addezio, Michela
Meo, Francesca
Scampoli, Piera
Romano, Ferdinando
Staniscia, Tommaso
author_sort Di Martino, Giuseppe
collection PubMed
description Background and Objectives: The improved life expectancy was associated to the increased in the incidence of hip fractures among elderly people. Subjects suffering hip fractures frequently show concomitant conditions causing prolonged lengths of stay and higher in-hospital mortality. The knowledge of factors associated to in-hospital mortality or adverse events can help healthcare providers improve patients’ outcomes and management. The aim of this study was to develop a score to predict in-hospital mortality among hip fractured patients. Materials and Methods: Cases were selected from hospital admissions that occurred during the period 2006–2015 in Abruzzo region, Italy. The study population was split into two random samples in order to evaluate the accuracy of prediction models. A multivariate logistic regression was performed in order to identify factors associated to in-hospital mortality. All diagnoses significantly associated to in-hospital mortality were included in the final model. Results: The PRIMOF ranged between 0 and 27 and was divided into four risk categories to allow the score interpretation. An increase in odds ratio values with the increase in PRIMOF score was reported in both study groups. Conclusions: This study showed that a simple score based on the patient’ clinical comorbidities was able to stratify the risk of hip-fractured patients in terms of in-hospital mortality.
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spelling pubmed-94126932022-08-27 Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score Di Martino, Giuseppe Di Giovanni, Pamela Cedrone, Fabrizio D’Addezio, Michela Meo, Francesca Scampoli, Piera Romano, Ferdinando Staniscia, Tommaso Medicina (Kaunas) Article Background and Objectives: The improved life expectancy was associated to the increased in the incidence of hip fractures among elderly people. Subjects suffering hip fractures frequently show concomitant conditions causing prolonged lengths of stay and higher in-hospital mortality. The knowledge of factors associated to in-hospital mortality or adverse events can help healthcare providers improve patients’ outcomes and management. The aim of this study was to develop a score to predict in-hospital mortality among hip fractured patients. Materials and Methods: Cases were selected from hospital admissions that occurred during the period 2006–2015 in Abruzzo region, Italy. The study population was split into two random samples in order to evaluate the accuracy of prediction models. A multivariate logistic regression was performed in order to identify factors associated to in-hospital mortality. All diagnoses significantly associated to in-hospital mortality were included in the final model. Results: The PRIMOF ranged between 0 and 27 and was divided into four risk categories to allow the score interpretation. An increase in odds ratio values with the increase in PRIMOF score was reported in both study groups. Conclusions: This study showed that a simple score based on the patient’ clinical comorbidities was able to stratify the risk of hip-fractured patients in terms of in-hospital mortality. MDPI 2022-08-11 /pmc/articles/PMC9412693/ /pubmed/36013549 http://dx.doi.org/10.3390/medicina58081082 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Di Martino, Giuseppe
Di Giovanni, Pamela
Cedrone, Fabrizio
D’Addezio, Michela
Meo, Francesca
Scampoli, Piera
Romano, Ferdinando
Staniscia, Tommaso
Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score
title Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score
title_full Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score
title_fullStr Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score
title_full_unstemmed Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score
title_short Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score
title_sort development and validation of a new tool in predicting in-hospital mortality for hip-fractured patients: the primof score
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412693/
https://www.ncbi.nlm.nih.gov/pubmed/36013549
http://dx.doi.org/10.3390/medicina58081082
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