The Impact of Epitranscriptomics on Antiviral Innate Immunity

Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycl...

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Detalles Bibliográficos
Autores principales: Mersinoglu, Beril, Cristinelli, Sara, Ciuffi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412694/
https://www.ncbi.nlm.nih.gov/pubmed/36016289
http://dx.doi.org/10.3390/v14081666
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author Mersinoglu, Beril
Cristinelli, Sara
Ciuffi, Angela
author_facet Mersinoglu, Beril
Cristinelli, Sara
Ciuffi, Angela
author_sort Mersinoglu, Beril
collection PubMed
description Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycle itself, acting on viral or cellular proteins promoting replication, or impacting the innate antiviral response of the host cell, the latter being the focus of the present review.
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spelling pubmed-94126942022-08-27 The Impact of Epitranscriptomics on Antiviral Innate Immunity Mersinoglu, Beril Cristinelli, Sara Ciuffi, Angela Viruses Review Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycle itself, acting on viral or cellular proteins promoting replication, or impacting the innate antiviral response of the host cell, the latter being the focus of the present review. MDPI 2022-07-28 /pmc/articles/PMC9412694/ /pubmed/36016289 http://dx.doi.org/10.3390/v14081666 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mersinoglu, Beril
Cristinelli, Sara
Ciuffi, Angela
The Impact of Epitranscriptomics on Antiviral Innate Immunity
title The Impact of Epitranscriptomics on Antiviral Innate Immunity
title_full The Impact of Epitranscriptomics on Antiviral Innate Immunity
title_fullStr The Impact of Epitranscriptomics on Antiviral Innate Immunity
title_full_unstemmed The Impact of Epitranscriptomics on Antiviral Innate Immunity
title_short The Impact of Epitranscriptomics on Antiviral Innate Immunity
title_sort impact of epitranscriptomics on antiviral innate immunity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412694/
https://www.ncbi.nlm.nih.gov/pubmed/36016289
http://dx.doi.org/10.3390/v14081666
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