Poly(trehalose methacrylate) as an Excipient for Insulin Stabilization: Mechanism and Safety

[Image: see text] Insulin, the oldest U.S. Food and Drug Administration (FDA)-approved recombinant protein and a World Health Organization (WHO) essential medicine for treating diabetes globally, faces challenges due to its storage instability. One approach to stabilize insulin is the addition of po...

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Autores principales: Gelb, Madeline B., Messina, Kathryn M. M., Vinciguerra, Daniele, Ko, Jeong Hoon, Collins, Jeffrey, Tamboline, Mikayla, Xu, Shili, Ibarrondo, F. Javier, Maynard, Heather D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412841/
https://www.ncbi.nlm.nih.gov/pubmed/35968684
http://dx.doi.org/10.1021/acsami.2c09301

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