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Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats
BACKGROUND: Glucagon-like peptide-1 (GLP1) is an endogenous peptide that regulates blood glucose level. But its susceptibility to rapid metabolic degradation limits its therapeutic use. AIM: To prepare GLP1-encapsulated nanosize particle with controlled release property to improve the systemic half-...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412859/ https://www.ncbi.nlm.nih.gov/pubmed/36159222 http://dx.doi.org/10.4239/wjd.v13.i8.613 |