B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema

Emphysema results in destruction of alveolar walls and enlargement of lung airspaces and has been shown to develop during helminth infections through IL-4R-independent mechanisms. We examined whether interleukin 17A (IL-17A) may instead modulate development of emphysematous pathology in mice infecte...

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Detalles Bibliográficos
Autores principales: Chen, Fei, Wu, Wenhui, Jin, Lianhua, Millman, Ariel, Palma, Mark, El-Naccache, Darine W., Lothstein, Katherine E., Dong, Chen, Edelblum, Karen L., Gause, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413029/
https://www.ncbi.nlm.nih.gov/pubmed/30517865
http://dx.doi.org/10.1016/j.celrep.2018.11.038

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