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Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response
BACKGROUND: The existence of immunologically ‘cold tumors’ frequently found across a wide spectrum of tumor types represents a significant challenge for cancer immunotherapy. Cold tumors have poor baseline pan-leukocyte infiltration, including a low prevalence of cytotoxic lymphocytes, and not surpr...
Autores principales: | Ahmed, Kazi Mokim, Veeramachaneni, Ratna, Deng, Defeng, Putluri, Nagireddy, Putluri, Vasanta, Cardenas, Maria F, Wheeler, David A, Decker, William K, Frederick, Andy I, Kazi, Sawad, Sikora, Andrew G, Sandulache, Vlad C, Frederick, Mitchell J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413193/ https://www.ncbi.nlm.nih.gov/pubmed/36002187 http://dx.doi.org/10.1136/jitc-2022-004752 |
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