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Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles

The pandemic situation caused by coronavirus clearly demonstrated the need for alternatives able to protect the respiratory tract and inactivate the infectious agents. Based on this, antibacterial face-mask filters of polycaprolactone (PCL) dopped with magnesium oxide (MgO) and copper oxide (CuO) na...

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Autores principales: Ferreira, Carolina A. M., Guerreiro, Sara F. C., Valente, Joana F. A., Patrício, Tatiana M. F., Alves, Nuno, Mateus, Artur, Dias, Juliana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413239/
https://www.ncbi.nlm.nih.gov/pubmed/36015586
http://dx.doi.org/10.3390/polym14163329
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author Ferreira, Carolina A. M.
Guerreiro, Sara F. C.
Valente, Joana F. A.
Patrício, Tatiana M. F.
Alves, Nuno
Mateus, Artur
Dias, Juliana R.
author_facet Ferreira, Carolina A. M.
Guerreiro, Sara F. C.
Valente, Joana F. A.
Patrício, Tatiana M. F.
Alves, Nuno
Mateus, Artur
Dias, Juliana R.
author_sort Ferreira, Carolina A. M.
collection PubMed
description The pandemic situation caused by coronavirus clearly demonstrated the need for alternatives able to protect the respiratory tract and inactivate the infectious agents. Based on this, antibacterial face-mask filters of polycaprolactone (PCL) dopped with magnesium oxide (MgO) and copper oxide (CuO) nanoparticles (NPs) were produced using an electrospinning technique. A morphological analysis of electrospun meshes evaluated the success of nanoparticles’ incorporation as well as the average fibers’ diameters (481 ± 272 nm). The performance of electrospun nanofibers was also assessed in terms of tensile strength (0.88 ± 0.25 MPa), water vapor permeability (11,178.66 ± 35.78 g·m(−2)·day(−1)), stability under wet conditions and antibacterial activity according to the standard guidelines. The filters showed structural stability up to 2 h of washing and improved antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) for optimized concentrations of MgO and CuO NPs. Overall, electrospun meshes with antibacterial activity were successfully developed for advanced filtering applications.
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spelling pubmed-94132392022-08-27 Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles Ferreira, Carolina A. M. Guerreiro, Sara F. C. Valente, Joana F. A. Patrício, Tatiana M. F. Alves, Nuno Mateus, Artur Dias, Juliana R. Polymers (Basel) Article The pandemic situation caused by coronavirus clearly demonstrated the need for alternatives able to protect the respiratory tract and inactivate the infectious agents. Based on this, antibacterial face-mask filters of polycaprolactone (PCL) dopped with magnesium oxide (MgO) and copper oxide (CuO) nanoparticles (NPs) were produced using an electrospinning technique. A morphological analysis of electrospun meshes evaluated the success of nanoparticles’ incorporation as well as the average fibers’ diameters (481 ± 272 nm). The performance of electrospun nanofibers was also assessed in terms of tensile strength (0.88 ± 0.25 MPa), water vapor permeability (11,178.66 ± 35.78 g·m(−2)·day(−1)), stability under wet conditions and antibacterial activity according to the standard guidelines. The filters showed structural stability up to 2 h of washing and improved antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) for optimized concentrations of MgO and CuO NPs. Overall, electrospun meshes with antibacterial activity were successfully developed for advanced filtering applications. MDPI 2022-08-16 /pmc/articles/PMC9413239/ /pubmed/36015586 http://dx.doi.org/10.3390/polym14163329 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ferreira, Carolina A. M.
Guerreiro, Sara F. C.
Valente, Joana F. A.
Patrício, Tatiana M. F.
Alves, Nuno
Mateus, Artur
Dias, Juliana R.
Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles
title Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles
title_full Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles
title_fullStr Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles
title_full_unstemmed Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles
title_short Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles
title_sort advanced face mask filters based on pcl electrospun meshes dopped with antimicrobial mgo and cuo nanoparticles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413239/
https://www.ncbi.nlm.nih.gov/pubmed/36015586
http://dx.doi.org/10.3390/polym14163329
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