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Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis
Background Soft-tissue sarcomas (STSs) are a rare heterogeneous group of tumors. Good functional results can be achieved with tumor excision in combination with suitable supplemental adjuvant therapies if needed. This study aimed to investigate the outcomes of wide resection of STS of the extremitie...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413370/ https://www.ncbi.nlm.nih.gov/pubmed/36042997 http://dx.doi.org/10.7759/cureus.27329 |
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author | Sheoran, Ajay Garg, Abhishek Yadav, Umesh Kundu, Zile Singh Sherawat, Ravi Singla, Mohit Nemani, Mudit Wason, Deepender Kulaar, Harshdeep Singh Singha, Sabuj Baran |
author_facet | Sheoran, Ajay Garg, Abhishek Yadav, Umesh Kundu, Zile Singh Sherawat, Ravi Singla, Mohit Nemani, Mudit Wason, Deepender Kulaar, Harshdeep Singh Singha, Sabuj Baran |
author_sort | Sheoran, Ajay |
collection | PubMed |
description | Background Soft-tissue sarcomas (STSs) are a rare heterogeneous group of tumors. Good functional results can be achieved with tumor excision in combination with suitable supplemental adjuvant therapies if needed. This study aimed to investigate the outcomes of wide resection of STS of the extremities. Methodology In this retrospective study, a total of 139 patients diagnosed with STS of the extremities by radiological and/or histopathological study/biopsy were included. All patients irrespective of metastasis were included. Results The mean age of the patients in our study was 43.5 ± 18.89 years. Overall, the mean tumor size was found to be 11.81 ± 6.218 cm. Malignant fibrous histiocytoma was the most common histology encountered (41%). Synovial sarcoma was the second most common histology encountered (14.38%). Recurrence was observed in 14 (10.1%) patients. The overall survival was 64.7% in our study. Conclusions The surgical margin achieved during the surgery is the most detrimental factor in local tumor control, and the overall survival of the patient after resection mainly depends on the stage of the tumor. |
format | Online Article Text |
id | pubmed-9413370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-94133702022-08-29 Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis Sheoran, Ajay Garg, Abhishek Yadav, Umesh Kundu, Zile Singh Sherawat, Ravi Singla, Mohit Nemani, Mudit Wason, Deepender Kulaar, Harshdeep Singh Singha, Sabuj Baran Cureus Oncology Background Soft-tissue sarcomas (STSs) are a rare heterogeneous group of tumors. Good functional results can be achieved with tumor excision in combination with suitable supplemental adjuvant therapies if needed. This study aimed to investigate the outcomes of wide resection of STS of the extremities. Methodology In this retrospective study, a total of 139 patients diagnosed with STS of the extremities by radiological and/or histopathological study/biopsy were included. All patients irrespective of metastasis were included. Results The mean age of the patients in our study was 43.5 ± 18.89 years. Overall, the mean tumor size was found to be 11.81 ± 6.218 cm. Malignant fibrous histiocytoma was the most common histology encountered (41%). Synovial sarcoma was the second most common histology encountered (14.38%). Recurrence was observed in 14 (10.1%) patients. The overall survival was 64.7% in our study. Conclusions The surgical margin achieved during the surgery is the most detrimental factor in local tumor control, and the overall survival of the patient after resection mainly depends on the stage of the tumor. Cureus 2022-07-27 /pmc/articles/PMC9413370/ /pubmed/36042997 http://dx.doi.org/10.7759/cureus.27329 Text en Copyright © 2022, Sheoran et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Oncology Sheoran, Ajay Garg, Abhishek Yadav, Umesh Kundu, Zile Singh Sherawat, Ravi Singla, Mohit Nemani, Mudit Wason, Deepender Kulaar, Harshdeep Singh Singha, Sabuj Baran Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis |
title | Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis |
title_full | Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis |
title_fullStr | Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis |
title_full_unstemmed | Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis |
title_short | Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis |
title_sort | outcomes of wide resection of soft-tissue sarcoma of the extremity: a retrospective analysis |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413370/ https://www.ncbi.nlm.nih.gov/pubmed/36042997 http://dx.doi.org/10.7759/cureus.27329 |
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