mRNA-Loaded Lipid Nanoparticles Targeting Dendritic Cells for Cancer Immunotherapy

Dendritic cells (DCs) are attractive antigen-presenting cells to be targeted for vaccinations. However, the systemic delivery of mRNA to DCs is hampered by technical challenges. We recently reported that it is possible to regulate the size of RNA-loaded lipid nanoparticles (LNPs) to over 200 nm with...

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Detalles Bibliográficos
Autores principales: Sasaki, Kosuke, Sato, Yusuke, Okuda, Kento, Iwakawa, Kazuki, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413374/
https://www.ncbi.nlm.nih.gov/pubmed/36015198
http://dx.doi.org/10.3390/pharmaceutics14081572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413374/
https://www.ncbi.nlm.nih.gov/pubmed/36015198
http://dx.doi.org/10.3390/pharmaceutics14081572

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