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Leveraging Substrate Promiscuity of a Radical S-Adenosyl-L-methionine RiPP Maturase toward Intramolecular Peptide Cross-Linking Applications

[Image: see text] Radical S-adenosyl-l-methionine (RS) enzymes operate on a variety of substrates and catalyze a wide range of complex radical-mediated transformations. Radical non-α-carbon thioether peptides (ranthipeptides) are a class of ribosomally synthesized and post-translationally modified p...

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Detalles Bibliográficos
Autores principales:	Eastman, Karsten A. S., Kincannon, William M., Bandarian, Vahe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413430/ https://www.ncbi.nlm.nih.gov/pubmed/36032765 http://dx.doi.org/10.1021/acscentsci.2c00501

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