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Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment

[Image: see text] Tumor immune microenvironment (TIME) regulators are promising cancer immunotherapeutic targets. IGF2BP1, as a crucial N(6)-methyladenosine (m(6)A) reader protein, recognizes m(6)A target transcripts, ultimately leading to cancer development. However, currently, the biological funct...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Guo, Qiang, Yang, Heng, Zhang, Xiao-Wen, Feng, Na, Wang, Jing-Kang, Liu, Ting-Ting, Zeng, Ke-Wu, Tu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413439/
https://www.ncbi.nlm.nih.gov/pubmed/36032766
http://dx.doi.org/10.1021/acscentsci.2c00107