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Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan

SIMPLE SUMMARY: Mastitis is an inflammation of the mammary gland that occurs in response to adverse mechanical, physical, chemical and biological factors. The use of antibiotics as a treatment has a negative impact on milk quality. This paper proposes the treatment of mastitis with a drug that conta...

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Autores principales: Mukhamadieva, Nurzhamal, Julanov, Mardan, Zainettinova, Dinara, Stefanik, Vasyl, Nurzhumanova, Zhanat, Mukataev, Aitbek, Suychinov, Anuarbek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413477/
https://www.ncbi.nlm.nih.gov/pubmed/36006312
http://dx.doi.org/10.3390/vetsci9080398
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author Mukhamadieva, Nurzhamal
Julanov, Mardan
Zainettinova, Dinara
Stefanik, Vasyl
Nurzhumanova, Zhanat
Mukataev, Aitbek
Suychinov, Anuarbek
author_facet Mukhamadieva, Nurzhamal
Julanov, Mardan
Zainettinova, Dinara
Stefanik, Vasyl
Nurzhumanova, Zhanat
Mukataev, Aitbek
Suychinov, Anuarbek
author_sort Mukhamadieva, Nurzhamal
collection PubMed
description SIMPLE SUMMARY: Mastitis is an inflammation of the mammary gland that occurs in response to adverse mechanical, physical, chemical and biological factors. The use of antibiotics as a treatment has a negative impact on milk quality. This paper proposes the treatment of mastitis with a drug that contains natural, environmentally friendly and pharmacologically active preparations. The inclusion of the preparation into the scheme of treatment allows to treat effectively inflammatory processes in the udder of cows and restore their productivity with minimal time and expenses. The drug has anti-inflammatory, antimicrobial and stimulating healing effects. ABSTRACT: In the present work, the prevalence, etiological factors and effective treatment scheme of mastitis in cows of dairy farms “Balke” and “Madi-R” in Eastern Kazakhstan were investigated. In total, 210 heads were investigated on two farms. The incidence of mastitis in cows on dairy farms is not the same in different years. Average clinical mastitis was detected in 35.4% of cows in 2016, 19.6% in 2017, 28.5% in 2018, and in 2019 in 16.4% of cows. The prevalence rates of subclinical mastitis by year had some differences. So, in 2016—36.5% of cows, then in 2017—21.5%, 2018—19.3% and in 2019—22.6%. In cows with udder inflammation, serum calcium 9.37 ± 0.15 mg/% with a range of 8.0 to 10.8 mg/%, phosphorus 3.58 ± 0.07 mg/% (3.0 to 4.3 mg/%), reserve alkalinity 363.46 ± 6.69 mg/% (320 to 440), carotene 0.49 ± 0.03 mg/% (0.220 to 0.988 mg/%), which are in the lower limit of physiological parameters. The drug “Dorob” was tested during the study of comparative effectiveness of treatment methods. The results of the study showed that this drug has anti-inflammatory, antimicrobial and stimulating healing actions. The treatment of the sick cows with catarrhal mastitis has shown that a total of 8 cows have recovered in the control group and 10 cows in the experimental group with the preparation “Dorob”. The period of recovery in the control group was 8.8 ± 0.39, and in the experimental group—6.2 ± 0.28 (p < 0.05). The drug does not contain antibiotics and hormonal preparations. The inclusion of the drug in the scheme of treatment allows for effectively treating inflammatory processes in the udder of cows and restoring their productivity with minimal cost of time and money.
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spelling pubmed-94134772022-08-27 Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan Mukhamadieva, Nurzhamal Julanov, Mardan Zainettinova, Dinara Stefanik, Vasyl Nurzhumanova, Zhanat Mukataev, Aitbek Suychinov, Anuarbek Vet Sci Article SIMPLE SUMMARY: Mastitis is an inflammation of the mammary gland that occurs in response to adverse mechanical, physical, chemical and biological factors. The use of antibiotics as a treatment has a negative impact on milk quality. This paper proposes the treatment of mastitis with a drug that contains natural, environmentally friendly and pharmacologically active preparations. The inclusion of the preparation into the scheme of treatment allows to treat effectively inflammatory processes in the udder of cows and restore their productivity with minimal time and expenses. The drug has anti-inflammatory, antimicrobial and stimulating healing effects. ABSTRACT: In the present work, the prevalence, etiological factors and effective treatment scheme of mastitis in cows of dairy farms “Balke” and “Madi-R” in Eastern Kazakhstan were investigated. In total, 210 heads were investigated on two farms. The incidence of mastitis in cows on dairy farms is not the same in different years. Average clinical mastitis was detected in 35.4% of cows in 2016, 19.6% in 2017, 28.5% in 2018, and in 2019 in 16.4% of cows. The prevalence rates of subclinical mastitis by year had some differences. So, in 2016—36.5% of cows, then in 2017—21.5%, 2018—19.3% and in 2019—22.6%. In cows with udder inflammation, serum calcium 9.37 ± 0.15 mg/% with a range of 8.0 to 10.8 mg/%, phosphorus 3.58 ± 0.07 mg/% (3.0 to 4.3 mg/%), reserve alkalinity 363.46 ± 6.69 mg/% (320 to 440), carotene 0.49 ± 0.03 mg/% (0.220 to 0.988 mg/%), which are in the lower limit of physiological parameters. The drug “Dorob” was tested during the study of comparative effectiveness of treatment methods. The results of the study showed that this drug has anti-inflammatory, antimicrobial and stimulating healing actions. The treatment of the sick cows with catarrhal mastitis has shown that a total of 8 cows have recovered in the control group and 10 cows in the experimental group with the preparation “Dorob”. The period of recovery in the control group was 8.8 ± 0.39, and in the experimental group—6.2 ± 0.28 (p < 0.05). The drug does not contain antibiotics and hormonal preparations. The inclusion of the drug in the scheme of treatment allows for effectively treating inflammatory processes in the udder of cows and restoring their productivity with minimal cost of time and money. MDPI 2022-07-30 /pmc/articles/PMC9413477/ /pubmed/36006312 http://dx.doi.org/10.3390/vetsci9080398 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mukhamadieva, Nurzhamal
Julanov, Mardan
Zainettinova, Dinara
Stefanik, Vasyl
Nurzhumanova, Zhanat
Mukataev, Aitbek
Suychinov, Anuarbek
Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
title Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
title_full Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
title_fullStr Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
title_full_unstemmed Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
title_short Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
title_sort prevalence, diagnosis and improving the effectiveness of therapy of mastitis in cows of dairy farms in east kazakhstan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413477/
https://www.ncbi.nlm.nih.gov/pubmed/36006312
http://dx.doi.org/10.3390/vetsci9080398
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