Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood–Brain Barrier

A proton-coupled organic cation (H(+)/OC) antiporter working at the blood–brain barrier (BBB) in humans and rodents is thought to be a promising candidate for the efficient delivery of cationic drugs to the brain. Therefore, it is important to identify the molecular entity that exhibits this activit...

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Detalles Bibliográficos
Autores principales: Kurosawa, Toshiki, Tega, Yuma, Uchida, Yasuo, Higuchi, Kei, Tabata, Hidetsugu, Sumiyoshi, Takaaki, Kubo, Yoshiyuki, Terasaki, Tetsuya, Deguchi, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413594/
https://www.ncbi.nlm.nih.gov/pubmed/36015309
http://dx.doi.org/10.3390/pharmaceutics14081683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413594/
https://www.ncbi.nlm.nih.gov/pubmed/36015309
http://dx.doi.org/10.3390/pharmaceutics14081683

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