Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape

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Consecutive waves of SARS-CoV-2 infection have been driven in part by the repeated emergence of variants with mutations that confer resistance to neutralizing antibodies Nevertheless, prolonged or repeated antigen exposure generates diverse memory B-cells that can produce affinity matured receptor b...

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Detalles Bibliográficos
Autores principales: Witte, Leander, Baharani, Viren, Schmidt, Fabian, Wang, Zijun, Cho, Alice, Raspe, Raphael, Guzman-Cardozo, Maria C., Muecksch, Frauke, Gaebler, Christian, Caskey, Marina, Nussenzweig, Michel C., Hatziioannou, Theodora, Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413706/
https://www.ncbi.nlm.nih.gov/pubmed/36032981
http://dx.doi.org/10.1101/2022.08.17.504313
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