cGAS-STING-mediated IFNI Response in Host Defense and Neuroinflammatory Diseases

The presence of foreign or misplaced nucleic acids is a dangerous signal that triggers innate immune responses by activating cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) and binding to its downstream signaling effector stimulator of interferon genes (STING). Then the cGAS-STING pathway activa...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Lai, Chuan, Su, Ying, Bao, Wen Dai, Yang, Liu Nan, Xu, Ping-Ping, Zhu, Ling-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413793/
https://www.ncbi.nlm.nih.gov/pubmed/34561985
http://dx.doi.org/10.2174/1570159X19666210924110144

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