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What Works for One May Not Work for Another: A New Warning for Modafinil

Narcolepsy is a clinical syndrome of hypothalamic disorder characterized by several sleep-wake disorders. The most common features include daytime sleepiness associated with hallucinations (hypnagogic and hypnopompic hallucinations) at the transition time of sleep-wake time, cataplexy or sudden loss...

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Detalles Bibliográficos
Autores principales: Kim, Harim, Ayele, Girma M, Atalay, Rediet T, Hussien, Siham, Tewoldemedhin, Bereket, Michael, Miriam B, Scharf, Steven M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413809/
https://www.ncbi.nlm.nih.gov/pubmed/36043022
http://dx.doi.org/10.7759/cureus.27287
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author Kim, Harim
Ayele, Girma M
Atalay, Rediet T
Hussien, Siham
Tewoldemedhin, Bereket
Michael, Miriam B
Scharf, Steven M
author_facet Kim, Harim
Ayele, Girma M
Atalay, Rediet T
Hussien, Siham
Tewoldemedhin, Bereket
Michael, Miriam B
Scharf, Steven M
author_sort Kim, Harim
collection PubMed
description Narcolepsy is a clinical syndrome of hypothalamic disorder characterized by several sleep-wake disorders. The most common features include daytime sleepiness associated with hallucinations (hypnagogic and hypnopompic hallucinations) at the transition time of sleep-wake time, cataplexy or sudden loss of muscle tone, and sleep paralysis. We present a case of a patient affected with both narcolepsy and postural orthostatic tachycardia syndrome (POTS). POTS is a rare disorder characterized by orthostatic intolerance and abnormal autonomic response while sustaining an upright posture. In this case report, we highlight the impact of POTS on the choice of pharmacotherapy for narcolepsy. 
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spelling pubmed-94138092022-08-29 What Works for One May Not Work for Another: A New Warning for Modafinil Kim, Harim Ayele, Girma M Atalay, Rediet T Hussien, Siham Tewoldemedhin, Bereket Michael, Miriam B Scharf, Steven M Cureus Family/General Practice Narcolepsy is a clinical syndrome of hypothalamic disorder characterized by several sleep-wake disorders. The most common features include daytime sleepiness associated with hallucinations (hypnagogic and hypnopompic hallucinations) at the transition time of sleep-wake time, cataplexy or sudden loss of muscle tone, and sleep paralysis. We present a case of a patient affected with both narcolepsy and postural orthostatic tachycardia syndrome (POTS). POTS is a rare disorder characterized by orthostatic intolerance and abnormal autonomic response while sustaining an upright posture. In this case report, we highlight the impact of POTS on the choice of pharmacotherapy for narcolepsy.  Cureus 2022-07-26 /pmc/articles/PMC9413809/ /pubmed/36043022 http://dx.doi.org/10.7759/cureus.27287 Text en Copyright © 2022, Kim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Kim, Harim
Ayele, Girma M
Atalay, Rediet T
Hussien, Siham
Tewoldemedhin, Bereket
Michael, Miriam B
Scharf, Steven M
What Works for One May Not Work for Another: A New Warning for Modafinil
title What Works for One May Not Work for Another: A New Warning for Modafinil
title_full What Works for One May Not Work for Another: A New Warning for Modafinil
title_fullStr What Works for One May Not Work for Another: A New Warning for Modafinil
title_full_unstemmed What Works for One May Not Work for Another: A New Warning for Modafinil
title_short What Works for One May Not Work for Another: A New Warning for Modafinil
title_sort what works for one may not work for another: a new warning for modafinil
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413809/
https://www.ncbi.nlm.nih.gov/pubmed/36043022
http://dx.doi.org/10.7759/cureus.27287
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