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Molecular Simulations Matching Denaturation Experiments for N(6)-Methyladenosine

[Image: see text] Post-transcriptional modifications are crucial for RNA function and can affect its structure and dynamics. Force-field-based classical molecular dynamics simulations are a fundamental tool to characterize biomolecular dynamics, and their application to RNA is flourishing. Here, we...

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Detalles Bibliográficos
Autores principales: Piomponi, Valerio, Fröhlking, Thorben, Bernetti, Mattia, Bussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413829/
https://www.ncbi.nlm.nih.gov/pubmed/36032773
http://dx.doi.org/10.1021/acscentsci.2c00565