SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution

BACKGROUND: Endogenous expression of L1 mRNA is the first step in an L1-initiated mutagenesis event. However, the contribution of individual cell types to patterns of organ-specific L1 mRNA expression remains poorly understood, especially at single-locus resolution. We introduce a method to quantify...

Descripción completa

Detalles Bibliográficos
Autores principales: Stow, Emily C., Baddoo, Melody, LaRosa, Alexis J., LaCoste, Dawn, Deininger, Prescott, Belancio, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413895/
https://www.ncbi.nlm.nih.gov/pubmed/36028901
http://dx.doi.org/10.1186/s13100-022-00276-0

Ejemplares similares

Ejemplares similares