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A transcriptomic analysis of cerebral microvessels reveals the involvement of Notch1 signaling in endothelial mitochondrial-dysfunction-dependent BBB disruption

BACKGROUND: Endothelial cells (ECs) in cerebral vessels are considered the primary targets in acute hemorrhagic brain injuries. EC dysfunction can aggravate neuronal injuries by causing secondary inflammatory responses and blood–brain barrier (BBB) disruption. Previous studies have reported that enh...

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Detalles Bibliográficos
Autores principales:	Lee, Min Joung, Zhu, Jiebo, An, Jong Hun, Lee, Seong Eun, Kim, Tae Yeon, Oh, Eungseok, Kang, Yea Eun, Chung, Woosuk, Heo, Jun Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414148/ https://www.ncbi.nlm.nih.gov/pubmed/36028880 http://dx.doi.org/10.1186/s12987-022-00363-7

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