In vitro atlas of dorsal spinal interneurons reveals Wnt signaling as a critical regulator of progenitor expansion

Restoring sensation after injury or disease requires a reproducible method for generating large quantities of bona fide somatosensory interneurons. Toward this goal, we assess the mechanisms by which dorsal spinal interneurons (dIs; dI1–dI6) can be derived from mouse embryonic stem cells (mESCs). Us...

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Detalles Bibliográficos
Autores principales: Gupta, Sandeep, Kawaguchi, Riki, Heinrichs, Eric, Gallardo, Salena, Castellanos, Stephanie, Mandric, Igor, Novitch, Bennett G., Butler, Samantha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414195/
https://www.ncbi.nlm.nih.gov/pubmed/35858555
http://dx.doi.org/10.1016/j.celrep.2022.111119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414195/
https://www.ncbi.nlm.nih.gov/pubmed/35858555
http://dx.doi.org/10.1016/j.celrep.2022.111119

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