Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening Initiative

AURORA aims to study the processes of relapse in metastatic breast cancer (MBC) by performing multi-omics profiling on paired primary tumors and early-course metastases. Among 381 patients (primary tumor and metastasis pairs: 252 targeted gene sequencing, 152 RNA sequencing, 67 single nucleotide pol...

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Detalles Bibliográficos
Autores principales: Aftimos, Philippe, Oliveira, Mafalda, Irrthum, Alexandre, Fumagalli, Debora, Sotiriou, Christos, Gal-Yam, Einav Nili, Robson, Mark E., Ndozeng, Justin, Di Leo, Angelo, Ciruelos, Eva M., de Azambuja, Evandro, Viale, Giuseppe, Scheepers, Elsemieke D., Curigliano, Giuseppe, Bliss, Judith M., Reis-Filho, Jorge S., Colleoni, Marco, Balic, Marija, Cardoso, Fatima, Albanell, Joan, Duhem, Caroline, Marreaud, Sandrine, Romagnoli, Dario, Rojas, Beatriz, Gombos, Andrea, Wildiers, Hans, Guerrero-Zotano, Angel, Hall, Peter, Bonetti, Andrea, Larsson, Karolina Fs, Degiorgis, Martina, Khodaverdi, Silvia, Greil, Richard, Sverrisdóttir, Ásgerdur, Paoli, Marta, Seyll, Ethel, Loibl, Sibylle, Linderholm, Barbro, Zoppoli, Gabriele, Davidson, Nancy E., Johannsson, Oskar Th, Bedard, Philippe L., Loi, Sherene, Knox, Susan, Cameron, David A., Harbeck, Nadia, Montoya, Maite Lasa, Brandão, Mariana, Vingiani, Andrea, Caballero, Carmela, Hilbers, Florentine S., Yates, Lucy R., Benelli, Matteo, Venet, David, Piccart, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414283/
https://www.ncbi.nlm.nih.gov/pubmed/34183353
http://dx.doi.org/10.1158/2159-8290.CD-20-1647

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