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Population Pharmacokinetics and Dose Optimization Based on Renal Function of Rivaroxaban in Thai Patients with Non-Valvular Atrial Fibrillation
Low-dose rivaroxaban has been used in Asian patients with direct oral anticoagulants (DOACs) eligible for atrial fibrillation (AF). However, there are few pharmacokinetic (PK) data in Thai patients to support precise dosing. This study aimed to develop a population PK model and determine the optimal...
Autores principales: | Singkham, Noppaket, Phrommintikul, Arintaya, Pacharasupa, Phongsathon, Norasetthada, Lalita, Gunaparn, Siriluck, Prasertwitayakij, Narawudt, Wongcharoen, Wanwarang, Punyawudho, Baralee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414338/ https://www.ncbi.nlm.nih.gov/pubmed/36015370 http://dx.doi.org/10.3390/pharmaceutics14081744 |
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