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PNPLA3 and TM6SF2 genetic variants and hepatic fibrosis and cirrhosis in Pakistani chronic hepatitis C patients: a genetic association study

BACKGROUND: The present study investigates if common missense functional variants p.I148M and p.E167K in PNPLA3 and TM6SF2 genes, respectively, associate with development of hepatic fibrosis and cirrhosis in a geographically novel cohort of Pakistani chronic hepatitis C (CHC) patients. METHODS: In t...

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Detalles Bibliográficos
Autores principales: Rauff, Bisma, Alzahrani, Badr, Chudhary, Shafiq A., Nasir, Bilal, Mahmood, Saqib, Bhinder, Munir Ahmad, Faheem, Muhammad, Amar, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414345/
https://www.ncbi.nlm.nih.gov/pubmed/36028802
http://dx.doi.org/10.1186/s12876-022-02469-6

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