A Human and Rhesus Macaque Interferon-Stimulated Gene Screen Shows That Over-Expression of ARHGEF3/XPLN Inhibits Replication of Hepatitis C Virus and Other Flavivirids

Natural hepatitis C virus (HCV) infection is restricted to humans, whereas other primates such as rhesus macaques are non-permissive for infection. To identify human and rhesus macaque genes that differ or share the ability to inhibit HCV replication, we conducted a medium-throughput screen of lenti...

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Detalles Bibliográficos
Autores principales: Bamford, Connor G. G., Aranday-Cortes, Elihu, Sanchez-Velazquez, Ricardo, Mullan, Catrina, Kohl, Alain, Patel, Arvind H., Wilson, Sam J., McLauchlan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414520/
https://www.ncbi.nlm.nih.gov/pubmed/36016278
http://dx.doi.org/10.3390/v14081655

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