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[1,5]-Hydride Shift Triggered N-Dealkylative Cyclization into 2-Oxo-1,2,3,4-tetrahydroquinoline-3-carboxylates via Boronate Complexes

A new simple one-pot two-step protocol for the synthesis of 2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate from 2-(2-(benzylamino)benzylidene)malonate under the action of BF3·Et2O was developed. It was shown that the reaction proceeds through the formation of a stable iminium intermediate containin...

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Detalles Bibliográficos
Autores principales:	Zaitseva, Elvira R., Ivanov, Dmitrii S., Smirnov, Alexander Yu., Mikhaylov, Andrey A., Baleeva, Nadezhda S., Baranov, Mikhail S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414529/ https://www.ncbi.nlm.nih.gov/pubmed/36014513 http://dx.doi.org/10.3390/molecules27165270

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