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CRISPR/Cas12a Coupling with Magnetic Nanoparticles and Cascaded Strand Displacement Reaction for Ultrasensitive Fluorescence Determination of Exosomal miR-21

Exosomal MicroRNA-21 (miRNA-21, miR-21) is significantly up-regulated in blood samples of patients with lung cancer. Exosomal-derived miR-21 can be used as a promising biomarker for the early diagnosis of lung cancer. This paper develops a fluorescent biosensor based on the combination of magnetic n...

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Detalles Bibliográficos
Autores principales:	Liu, Qing, Liu, Jingjian, He, Na, Zhang, Moli, Wu, Lun, Chen, Xiyu, Zhu, Jun, Ran, Fengying, Chen, Qinhua, Zhang, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414586/ https://www.ncbi.nlm.nih.gov/pubmed/36014577 http://dx.doi.org/10.3390/molecules27165338

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