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Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review

Brazil has the most incredible biodiversity globally and has a vast storehouse of molecules to be discovered. However, there are no pharmacological and phytochemical studies on most native plants. Parts of Schinopsis brasiliensis Engler, a tree from the Anacardiaceae family, are used by several trad...

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Autores principales: Barreto Linhares, Ladaha Pequeno Menna, Pereira, Bruna Vanessa Nunes, Dantas, Maria Karoline Gomes, Bezerra, Wislayne Mirelly da Silva, Viana-Marques, Daniela de Araújo, de Lima, Luiza Rayanna Amorim, Sette-de-Souza, Pedro Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414610/
https://www.ncbi.nlm.nih.gov/pubmed/36015176
http://dx.doi.org/10.3390/ph15081028
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author Barreto Linhares, Ladaha Pequeno Menna
Pereira, Bruna Vanessa Nunes
Dantas, Maria Karoline Gomes
Bezerra, Wislayne Mirelly da Silva
Viana-Marques, Daniela de Araújo
de Lima, Luiza Rayanna Amorim
Sette-de-Souza, Pedro Henrique
author_facet Barreto Linhares, Ladaha Pequeno Menna
Pereira, Bruna Vanessa Nunes
Dantas, Maria Karoline Gomes
Bezerra, Wislayne Mirelly da Silva
Viana-Marques, Daniela de Araújo
de Lima, Luiza Rayanna Amorim
Sette-de-Souza, Pedro Henrique
author_sort Barreto Linhares, Ladaha Pequeno Menna
collection PubMed
description Brazil has the most incredible biodiversity globally and has a vast storehouse of molecules to be discovered. However, there are no pharmacological and phytochemical studies on most native plants. Parts of Schinopsis brasiliensis Engler, a tree from the Anacardiaceae family, are used by several traditional communities to treat injuries and health problems. The objective of this scoping review was to summarize the pharmacological information about S. brasiliensis, from ethnobotanical to phytochemical and biological studies. Data collection concerning the geographical distribution of S. brasiliensis specimens was achieved through the Reflora Virtual Herbarium. The study’s protocol was drafted using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The search strategy used the keyword “Schinopsis brasiliensis” in the databases: PUBMED, EMBASE, SCOPUS, Science Direct, Web of Science, SciFinder, and SciELO. Rayyan was used for the selection of eligible studies. In total, 35 studies were included in the paper. The most recurrent therapeutic indications were for general pain, flu and inflammation. The bark was the most studied part of the plant. The most used preparation method was decoction and infusion, followed by syrup. Phytochemical investigations indicate the presence of tannins, flavonoids, phenols, and polyphenols. Most of the substances were found in the plant’s leaf and bark. Important biological activities were reported, such as antimicrobial, antioxidant, and anti-inflammatory. S. brasiliensis is used mainly by communities in the semi-arid region of northeastern Brazil to treat several diseases. Pharmacological and phytochemical studies together provide scientific support for the popular knowledge of the medicinal use of S. brasiliensis. In vitro and in vivo analyses reported antimicrobial, antioxidant, anti-inflammatory, antinociceptive, cytotoxic, photoprotective, preservative, molluscicidal, larvicidal, and pupicidal effects. It is essential to highlight the need for future studies that elucidate the mechanisms of action of these phytocompounds.
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spelling pubmed-94146102022-08-27 Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review Barreto Linhares, Ladaha Pequeno Menna Pereira, Bruna Vanessa Nunes Dantas, Maria Karoline Gomes Bezerra, Wislayne Mirelly da Silva Viana-Marques, Daniela de Araújo de Lima, Luiza Rayanna Amorim Sette-de-Souza, Pedro Henrique Pharmaceuticals (Basel) Systematic Review Brazil has the most incredible biodiversity globally and has a vast storehouse of molecules to be discovered. However, there are no pharmacological and phytochemical studies on most native plants. Parts of Schinopsis brasiliensis Engler, a tree from the Anacardiaceae family, are used by several traditional communities to treat injuries and health problems. The objective of this scoping review was to summarize the pharmacological information about S. brasiliensis, from ethnobotanical to phytochemical and biological studies. Data collection concerning the geographical distribution of S. brasiliensis specimens was achieved through the Reflora Virtual Herbarium. The study’s protocol was drafted using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The search strategy used the keyword “Schinopsis brasiliensis” in the databases: PUBMED, EMBASE, SCOPUS, Science Direct, Web of Science, SciFinder, and SciELO. Rayyan was used for the selection of eligible studies. In total, 35 studies were included in the paper. The most recurrent therapeutic indications were for general pain, flu and inflammation. The bark was the most studied part of the plant. The most used preparation method was decoction and infusion, followed by syrup. Phytochemical investigations indicate the presence of tannins, flavonoids, phenols, and polyphenols. Most of the substances were found in the plant’s leaf and bark. Important biological activities were reported, such as antimicrobial, antioxidant, and anti-inflammatory. S. brasiliensis is used mainly by communities in the semi-arid region of northeastern Brazil to treat several diseases. Pharmacological and phytochemical studies together provide scientific support for the popular knowledge of the medicinal use of S. brasiliensis. In vitro and in vivo analyses reported antimicrobial, antioxidant, anti-inflammatory, antinociceptive, cytotoxic, photoprotective, preservative, molluscicidal, larvicidal, and pupicidal effects. It is essential to highlight the need for future studies that elucidate the mechanisms of action of these phytocompounds. MDPI 2022-08-20 /pmc/articles/PMC9414610/ /pubmed/36015176 http://dx.doi.org/10.3390/ph15081028 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Barreto Linhares, Ladaha Pequeno Menna
Pereira, Bruna Vanessa Nunes
Dantas, Maria Karoline Gomes
Bezerra, Wislayne Mirelly da Silva
Viana-Marques, Daniela de Araújo
de Lima, Luiza Rayanna Amorim
Sette-de-Souza, Pedro Henrique
Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
title Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
title_full Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
title_fullStr Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
title_full_unstemmed Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
title_short Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
title_sort schinopsis brasiliensis engler—phytochemical properties, biological activities, and ethnomedicinal use: a scoping review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414610/
https://www.ncbi.nlm.nih.gov/pubmed/36015176
http://dx.doi.org/10.3390/ph15081028
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