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Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review
Brazil has the most incredible biodiversity globally and has a vast storehouse of molecules to be discovered. However, there are no pharmacological and phytochemical studies on most native plants. Parts of Schinopsis brasiliensis Engler, a tree from the Anacardiaceae family, are used by several trad...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414610/ https://www.ncbi.nlm.nih.gov/pubmed/36015176 http://dx.doi.org/10.3390/ph15081028 |
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author | Barreto Linhares, Ladaha Pequeno Menna Pereira, Bruna Vanessa Nunes Dantas, Maria Karoline Gomes Bezerra, Wislayne Mirelly da Silva Viana-Marques, Daniela de Araújo de Lima, Luiza Rayanna Amorim Sette-de-Souza, Pedro Henrique |
author_facet | Barreto Linhares, Ladaha Pequeno Menna Pereira, Bruna Vanessa Nunes Dantas, Maria Karoline Gomes Bezerra, Wislayne Mirelly da Silva Viana-Marques, Daniela de Araújo de Lima, Luiza Rayanna Amorim Sette-de-Souza, Pedro Henrique |
author_sort | Barreto Linhares, Ladaha Pequeno Menna |
collection | PubMed |
description | Brazil has the most incredible biodiversity globally and has a vast storehouse of molecules to be discovered. However, there are no pharmacological and phytochemical studies on most native plants. Parts of Schinopsis brasiliensis Engler, a tree from the Anacardiaceae family, are used by several traditional communities to treat injuries and health problems. The objective of this scoping review was to summarize the pharmacological information about S. brasiliensis, from ethnobotanical to phytochemical and biological studies. Data collection concerning the geographical distribution of S. brasiliensis specimens was achieved through the Reflora Virtual Herbarium. The study’s protocol was drafted using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The search strategy used the keyword “Schinopsis brasiliensis” in the databases: PUBMED, EMBASE, SCOPUS, Science Direct, Web of Science, SciFinder, and SciELO. Rayyan was used for the selection of eligible studies. In total, 35 studies were included in the paper. The most recurrent therapeutic indications were for general pain, flu and inflammation. The bark was the most studied part of the plant. The most used preparation method was decoction and infusion, followed by syrup. Phytochemical investigations indicate the presence of tannins, flavonoids, phenols, and polyphenols. Most of the substances were found in the plant’s leaf and bark. Important biological activities were reported, such as antimicrobial, antioxidant, and anti-inflammatory. S. brasiliensis is used mainly by communities in the semi-arid region of northeastern Brazil to treat several diseases. Pharmacological and phytochemical studies together provide scientific support for the popular knowledge of the medicinal use of S. brasiliensis. In vitro and in vivo analyses reported antimicrobial, antioxidant, anti-inflammatory, antinociceptive, cytotoxic, photoprotective, preservative, molluscicidal, larvicidal, and pupicidal effects. It is essential to highlight the need for future studies that elucidate the mechanisms of action of these phytocompounds. |
format | Online Article Text |
id | pubmed-9414610 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94146102022-08-27 Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review Barreto Linhares, Ladaha Pequeno Menna Pereira, Bruna Vanessa Nunes Dantas, Maria Karoline Gomes Bezerra, Wislayne Mirelly da Silva Viana-Marques, Daniela de Araújo de Lima, Luiza Rayanna Amorim Sette-de-Souza, Pedro Henrique Pharmaceuticals (Basel) Systematic Review Brazil has the most incredible biodiversity globally and has a vast storehouse of molecules to be discovered. However, there are no pharmacological and phytochemical studies on most native plants. Parts of Schinopsis brasiliensis Engler, a tree from the Anacardiaceae family, are used by several traditional communities to treat injuries and health problems. The objective of this scoping review was to summarize the pharmacological information about S. brasiliensis, from ethnobotanical to phytochemical and biological studies. Data collection concerning the geographical distribution of S. brasiliensis specimens was achieved through the Reflora Virtual Herbarium. The study’s protocol was drafted using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). The search strategy used the keyword “Schinopsis brasiliensis” in the databases: PUBMED, EMBASE, SCOPUS, Science Direct, Web of Science, SciFinder, and SciELO. Rayyan was used for the selection of eligible studies. In total, 35 studies were included in the paper. The most recurrent therapeutic indications were for general pain, flu and inflammation. The bark was the most studied part of the plant. The most used preparation method was decoction and infusion, followed by syrup. Phytochemical investigations indicate the presence of tannins, flavonoids, phenols, and polyphenols. Most of the substances were found in the plant’s leaf and bark. Important biological activities were reported, such as antimicrobial, antioxidant, and anti-inflammatory. S. brasiliensis is used mainly by communities in the semi-arid region of northeastern Brazil to treat several diseases. Pharmacological and phytochemical studies together provide scientific support for the popular knowledge of the medicinal use of S. brasiliensis. In vitro and in vivo analyses reported antimicrobial, antioxidant, anti-inflammatory, antinociceptive, cytotoxic, photoprotective, preservative, molluscicidal, larvicidal, and pupicidal effects. It is essential to highlight the need for future studies that elucidate the mechanisms of action of these phytocompounds. MDPI 2022-08-20 /pmc/articles/PMC9414610/ /pubmed/36015176 http://dx.doi.org/10.3390/ph15081028 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Barreto Linhares, Ladaha Pequeno Menna Pereira, Bruna Vanessa Nunes Dantas, Maria Karoline Gomes Bezerra, Wislayne Mirelly da Silva Viana-Marques, Daniela de Araújo de Lima, Luiza Rayanna Amorim Sette-de-Souza, Pedro Henrique Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review |
title | Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review |
title_full | Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review |
title_fullStr | Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review |
title_full_unstemmed | Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review |
title_short | Schinopsis brasiliensis Engler—Phytochemical Properties, Biological Activities, and Ethnomedicinal Use: A Scoping Review |
title_sort | schinopsis brasiliensis engler—phytochemical properties, biological activities, and ethnomedicinal use: a scoping review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414610/ https://www.ncbi.nlm.nih.gov/pubmed/36015176 http://dx.doi.org/10.3390/ph15081028 |
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