Development of a Well-Characterized Cynomolgus Macaque Model of Marburg Virus Disease for Support of Vaccine and Therapy Development

Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development. However, MARV has an average case fatality rate of approximately 50%,...

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Autores principales: Alfson, Kendra J., Goez-Gazi, Yenny, Gazi, Michal, Chou, Ying-Liang, Niemuth, Nancy A., Mattix, Marc E., Staples, Hilary M., Klaffke, Benjamin, Rodriguez, Gloria F., Bartley, Carmen, Ticer, Anysha, Clemmons, Elizabeth A., Dutton, John W., Griffiths, Anthony, Meister, Gabe T., Sanford, Daniel C., Cirimotich, Chris M., Carrion, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414819/
https://www.ncbi.nlm.nih.gov/pubmed/36016203
http://dx.doi.org/10.3390/vaccines10081314

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