Cholesterol-Lowering Effects of Asperidine B, a Pyrrolidine Derivative from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178: A Potential Cholesterol Absorption Inhibitor

Isolated secondary metabolites asperidine B (preussin) and asperidine C, produced by the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178, were found to exhibit inhibitory effects against 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase and oxidative stress in an in vitro assay. Whether or n...

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Detalles Bibliográficos
Autores principales: Ontawong, Atcharaporn, Duangjai, Acharaporn, Sukpondma, Yaowapa, Tadpetch, Kwanruthai, Muanprasat, Chatchai, Rukachaisirikul, Vatcharin, Inchai, Jakkapong, Vaddhanaphuti, Chutima S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414821/
https://www.ncbi.nlm.nih.gov/pubmed/36015103
http://dx.doi.org/10.3390/ph15080955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414821/
https://www.ncbi.nlm.nih.gov/pubmed/36015103
http://dx.doi.org/10.3390/ph15080955

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