Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective

Traditional Chinese medicine (TCM) has been used to treat diabetes for a long time, but its application has not been widely accepted due to unstandardized product quality and complex pharmacological mechanisms. The modernization of TCM is crucial for its further development, and in recent years the...

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Autores principales: Huang, Yinli, Lu, Jiahui, Zhao, Qihui, Chen, Junli, Dong, Wei, Lin, Minjie, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414875/
https://www.ncbi.nlm.nih.gov/pubmed/36014349
http://dx.doi.org/10.3390/molecules27165109
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author Huang, Yinli
Lu, Jiahui
Zhao, Qihui
Chen, Junli
Dong, Wei
Lin, Minjie
Zheng, Hong
author_facet Huang, Yinli
Lu, Jiahui
Zhao, Qihui
Chen, Junli
Dong, Wei
Lin, Minjie
Zheng, Hong
author_sort Huang, Yinli
collection PubMed
description Traditional Chinese medicine (TCM) has been used to treat diabetes for a long time, but its application has not been widely accepted due to unstandardized product quality and complex pharmacological mechanisms. The modernization of TCM is crucial for its further development, and in recent years the metabolomics technique has largely driven its modernization. This review focuses on the application of NMR-based metabolomics in diabetic therapy using TCM. We identified a series of metabolic pathways that altered significantly after TCM treatment, providing a better understanding of the metabolic mechanisms of TCM for diabetes care.
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spelling pubmed-94148752022-08-27 Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective Huang, Yinli Lu, Jiahui Zhao, Qihui Chen, Junli Dong, Wei Lin, Minjie Zheng, Hong Molecules Review Traditional Chinese medicine (TCM) has been used to treat diabetes for a long time, but its application has not been widely accepted due to unstandardized product quality and complex pharmacological mechanisms. The modernization of TCM is crucial for its further development, and in recent years the metabolomics technique has largely driven its modernization. This review focuses on the application of NMR-based metabolomics in diabetic therapy using TCM. We identified a series of metabolic pathways that altered significantly after TCM treatment, providing a better understanding of the metabolic mechanisms of TCM for diabetes care. MDPI 2022-08-11 /pmc/articles/PMC9414875/ /pubmed/36014349 http://dx.doi.org/10.3390/molecules27165109 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Huang, Yinli
Lu, Jiahui
Zhao, Qihui
Chen, Junli
Dong, Wei
Lin, Minjie
Zheng, Hong
Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
title Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
title_full Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
title_fullStr Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
title_full_unstemmed Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
title_short Potential Therapeutic Mechanism of Traditional Chinese Medicine on Diabetes in Rodents: A Review from an NMR-Based Metabolomics Perspective
title_sort potential therapeutic mechanism of traditional chinese medicine on diabetes in rodents: a review from an nmr-based metabolomics perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414875/
https://www.ncbi.nlm.nih.gov/pubmed/36014349
http://dx.doi.org/10.3390/molecules27165109
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