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Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds
In our aging society, the number of patients suffering from poorly healing bone defects increases. Bone morphogenetic proteins (BMPs) are used in the clinic to promote bone regeneration. However, poor control of BMP delivery and thus activity necessitates high doses, resulting in adverse effects and...
Autores principales: | Oude Egberink, Rik, Zegelaar, Helen M., El Boujnouni, Najoua, Versteeg, Elly M. M., Daamen, Willeke F., Brock, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414905/ https://www.ncbi.nlm.nih.gov/pubmed/36015245 http://dx.doi.org/10.3390/pharmaceutics14081619 |
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