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α-Glucosidase and α-Amylase Inhibitory Potentials of Quinoline–1,3,4-oxadiazole Conjugates Bearing 1,2,3-Triazole with Antioxidant Activity, Kinetic Studies, and Computational Validation
Diabetes mellitus (DM) is a multifaceted metabolic disorder that remains a major threat to global health security. Sadly, the clinical relevance of available drugs is burdened with an upsurge in adverse effects; hence, inhibiting the carbohydrate-hydrolyzing enzymes α-glucosidase and α-amylase while...
Autores principales: | Cele, Nosipho, Awolade, Paul, Seboletswe, Pule, Olofinsan, Kolawole, Islam, Md. Shahidul, Singh, Parvesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414972/ https://www.ncbi.nlm.nih.gov/pubmed/36015183 http://dx.doi.org/10.3390/ph15081035 |
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