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Use of staging for sex cord stromal tumours

Sex cord-stromal tumours (SCSTs) are rare ovarian cancers. As in the literature, only small case series or case reports are published, gathering solid evidence about their management is challenging. Surgery plays a pivotal role, and accurate staging is one of the most important prognostic factors. T...

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Autores principales: Negri, Serena, Grassi, Tommaso, Fruscio, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415218/
https://www.ncbi.nlm.nih.gov/pubmed/35849655
http://dx.doi.org/10.1097/CCO.0000000000000860
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author Negri, Serena
Grassi, Tommaso
Fruscio, Robert
author_facet Negri, Serena
Grassi, Tommaso
Fruscio, Robert
author_sort Negri, Serena
collection PubMed
description Sex cord-stromal tumours (SCSTs) are rare ovarian cancers. As in the literature, only small case series or case reports are published, gathering solid evidence about their management is challenging. Surgery plays a pivotal role, and accurate staging is one of the most important prognostic factors. This review focuses on the current evidence for surgical staging in the management of SCSTs. RECENT FINDINGS: Staging procedures have been inferred by epithelial ovarian cancers; however, they are often only partially performed, and most SCSTs therefore end up incompletely staged, raising the issue of the need for restaging or further treatments. In addition, some parts of the staging procedure have been questioned over the years, and lymphadenectomy is now considered unnecessary for SCSTs. The generally favourable prognosis of SCSTs, the introduction of minimally invasive surgery and fertility-sparing approaches is empowering the question of which staging procedures are beneficial for these patients. We reviewed the role of each staging procedure proposed by the guidelines in light of new scientific updates. SUMMARY: Surgical staging should always be performed. It includes peritoneal samplings (peritoneal washing, multiple peritoneal biopsies, omental biopsy and biopsy of any suspicious area), whereas lymphadenectomy could be omitted. Laparoscopy may be considered a feasible approach.
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spelling pubmed-94152182022-08-26 Use of staging for sex cord stromal tumours Negri, Serena Grassi, Tommaso Fruscio, Robert Curr Opin Oncol GYNECOLOGIC CANCER: Edited by Frédéric Amant and Christianne Lok Sex cord-stromal tumours (SCSTs) are rare ovarian cancers. As in the literature, only small case series or case reports are published, gathering solid evidence about their management is challenging. Surgery plays a pivotal role, and accurate staging is one of the most important prognostic factors. This review focuses on the current evidence for surgical staging in the management of SCSTs. RECENT FINDINGS: Staging procedures have been inferred by epithelial ovarian cancers; however, they are often only partially performed, and most SCSTs therefore end up incompletely staged, raising the issue of the need for restaging or further treatments. In addition, some parts of the staging procedure have been questioned over the years, and lymphadenectomy is now considered unnecessary for SCSTs. The generally favourable prognosis of SCSTs, the introduction of minimally invasive surgery and fertility-sparing approaches is empowering the question of which staging procedures are beneficial for these patients. We reviewed the role of each staging procedure proposed by the guidelines in light of new scientific updates. SUMMARY: Surgical staging should always be performed. It includes peritoneal samplings (peritoneal washing, multiple peritoneal biopsies, omental biopsy and biopsy of any suspicious area), whereas lymphadenectomy could be omitted. Laparoscopy may be considered a feasible approach. Lippincott Williams & Wilkins 2022-09 2022-07-16 /pmc/articles/PMC9415218/ /pubmed/35849655 http://dx.doi.org/10.1097/CCO.0000000000000860 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle GYNECOLOGIC CANCER: Edited by Frédéric Amant and Christianne Lok
Negri, Serena
Grassi, Tommaso
Fruscio, Robert
Use of staging for sex cord stromal tumours
title Use of staging for sex cord stromal tumours
title_full Use of staging for sex cord stromal tumours
title_fullStr Use of staging for sex cord stromal tumours
title_full_unstemmed Use of staging for sex cord stromal tumours
title_short Use of staging for sex cord stromal tumours
title_sort use of staging for sex cord stromal tumours
topic GYNECOLOGIC CANCER: Edited by Frédéric Amant and Christianne Lok
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415218/
https://www.ncbi.nlm.nih.gov/pubmed/35849655
http://dx.doi.org/10.1097/CCO.0000000000000860
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