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SARS-CoV-2 and MERS-CoV Spike Protein Binding Studies Support Stable Mimic of Bound 9-O-Acetylated Sialic Acids

Many disease-causing viruses target sialic acids (Sias), a class of nine-carbon sugars known to coat the surface of many cells, including those in the lungs. Human beta coronaviridae, known for causing respiratory tract diseases, often bind Sias, and some preferentially bind to those with 9-O-Ac-mod...

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Detalles Bibliográficos
Autores principales: Oh, Lisa, Varki, Ajit, Chen, Xi, Wang, Lee-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415320/
https://www.ncbi.nlm.nih.gov/pubmed/36014560
http://dx.doi.org/10.3390/molecules27165322

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