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Three-Dimensional Printing of an Apigenin-Loaded Mucoadhesive Film for Tailored Therapy to Oral Leukoplakia and the Chemopreventive Effect on a Rat Model of Oral Carcinogenesis
Oral leukoplakia, which presents as white lesions in the oral cavity, including on the tongue, is precancerous in nature. Conservative treatment is preferable, since surgical removal can markedly reduce the patient’s quality of life. In the present study, we focused on the flavonoid apigenin as a po...
Autores principales: | Takashima, Hiroyuki, Tagami, Tatsuaki, Kato, Shinichiro, Pae, Heeju, Ozeki, Tetsuya, Shibuya, Yasuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415331/ https://www.ncbi.nlm.nih.gov/pubmed/36015201 http://dx.doi.org/10.3390/pharmaceutics14081575 |
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