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Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs

Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translati...

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Autores principales: Sabit, Hussein, Abdel-Hakeem, Mohamed, Shoala, Tahsin, Abdel-Ghany, Shaimaa, Abdel-Latif, Mokhtar Mamdouh, Almulhim, Jawaher, Mansy, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415391/
https://www.ncbi.nlm.nih.gov/pubmed/36015192
http://dx.doi.org/10.3390/pharmaceutics14081566
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author Sabit, Hussein
Abdel-Hakeem, Mohamed
Shoala, Tahsin
Abdel-Ghany, Shaimaa
Abdel-Latif, Mokhtar Mamdouh
Almulhim, Jawaher
Mansy, Mohamed
author_facet Sabit, Hussein
Abdel-Hakeem, Mohamed
Shoala, Tahsin
Abdel-Ghany, Shaimaa
Abdel-Latif, Mokhtar Mamdouh
Almulhim, Jawaher
Mansy, Mohamed
author_sort Sabit, Hussein
collection PubMed
description Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translating nanomedicines from preclinical to clinical settings has been difficult. Rapid advancements in nanotechnology promise to enhance cancer therapies. Nanomedicine offers advanced targeting and multifunctionality. Nanoparticles (NPs) have several uses nowadays. They have been studied as drug transporters, tumor gene delivery agents, and imaging contrast agents. Nanomaterials based on organic, inorganic, lipid, or glycan substances and synthetic polymers have been used to enhance cancer therapies. This review focuses on polymeric nanoparticle delivery strategies for anticancer nanomedicines.
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spelling pubmed-94153912022-08-27 Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs Sabit, Hussein Abdel-Hakeem, Mohamed Shoala, Tahsin Abdel-Ghany, Shaimaa Abdel-Latif, Mokhtar Mamdouh Almulhim, Jawaher Mansy, Mohamed Pharmaceutics Review Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translating nanomedicines from preclinical to clinical settings has been difficult. Rapid advancements in nanotechnology promise to enhance cancer therapies. Nanomedicine offers advanced targeting and multifunctionality. Nanoparticles (NPs) have several uses nowadays. They have been studied as drug transporters, tumor gene delivery agents, and imaging contrast agents. Nanomaterials based on organic, inorganic, lipid, or glycan substances and synthetic polymers have been used to enhance cancer therapies. This review focuses on polymeric nanoparticle delivery strategies for anticancer nanomedicines. MDPI 2022-07-28 /pmc/articles/PMC9415391/ /pubmed/36015192 http://dx.doi.org/10.3390/pharmaceutics14081566 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sabit, Hussein
Abdel-Hakeem, Mohamed
Shoala, Tahsin
Abdel-Ghany, Shaimaa
Abdel-Latif, Mokhtar Mamdouh
Almulhim, Jawaher
Mansy, Mohamed
Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
title Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
title_full Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
title_fullStr Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
title_full_unstemmed Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
title_short Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
title_sort nanocarriers: a reliable tool for the delivery of anticancer drugs
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415391/
https://www.ncbi.nlm.nih.gov/pubmed/36015192
http://dx.doi.org/10.3390/pharmaceutics14081566
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