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Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs
Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translati...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415391/ https://www.ncbi.nlm.nih.gov/pubmed/36015192 http://dx.doi.org/10.3390/pharmaceutics14081566 |
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author | Sabit, Hussein Abdel-Hakeem, Mohamed Shoala, Tahsin Abdel-Ghany, Shaimaa Abdel-Latif, Mokhtar Mamdouh Almulhim, Jawaher Mansy, Mohamed |
author_facet | Sabit, Hussein Abdel-Hakeem, Mohamed Shoala, Tahsin Abdel-Ghany, Shaimaa Abdel-Latif, Mokhtar Mamdouh Almulhim, Jawaher Mansy, Mohamed |
author_sort | Sabit, Hussein |
collection | PubMed |
description | Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translating nanomedicines from preclinical to clinical settings has been difficult. Rapid advancements in nanotechnology promise to enhance cancer therapies. Nanomedicine offers advanced targeting and multifunctionality. Nanoparticles (NPs) have several uses nowadays. They have been studied as drug transporters, tumor gene delivery agents, and imaging contrast agents. Nanomaterials based on organic, inorganic, lipid, or glycan substances and synthetic polymers have been used to enhance cancer therapies. This review focuses on polymeric nanoparticle delivery strategies for anticancer nanomedicines. |
format | Online Article Text |
id | pubmed-9415391 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94153912022-08-27 Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs Sabit, Hussein Abdel-Hakeem, Mohamed Shoala, Tahsin Abdel-Ghany, Shaimaa Abdel-Latif, Mokhtar Mamdouh Almulhim, Jawaher Mansy, Mohamed Pharmaceutics Review Nanomedicines have gained popularity due to their potential therapeutic applications, especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer cells and enable prolonged drug release, reducing off-target toxicity and increasing therapeutic efficacy. However, translating nanomedicines from preclinical to clinical settings has been difficult. Rapid advancements in nanotechnology promise to enhance cancer therapies. Nanomedicine offers advanced targeting and multifunctionality. Nanoparticles (NPs) have several uses nowadays. They have been studied as drug transporters, tumor gene delivery agents, and imaging contrast agents. Nanomaterials based on organic, inorganic, lipid, or glycan substances and synthetic polymers have been used to enhance cancer therapies. This review focuses on polymeric nanoparticle delivery strategies for anticancer nanomedicines. MDPI 2022-07-28 /pmc/articles/PMC9415391/ /pubmed/36015192 http://dx.doi.org/10.3390/pharmaceutics14081566 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sabit, Hussein Abdel-Hakeem, Mohamed Shoala, Tahsin Abdel-Ghany, Shaimaa Abdel-Latif, Mokhtar Mamdouh Almulhim, Jawaher Mansy, Mohamed Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs |
title | Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs |
title_full | Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs |
title_fullStr | Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs |
title_full_unstemmed | Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs |
title_short | Nanocarriers: A Reliable Tool for the Delivery of Anticancer Drugs |
title_sort | nanocarriers: a reliable tool for the delivery of anticancer drugs |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415391/ https://www.ncbi.nlm.nih.gov/pubmed/36015192 http://dx.doi.org/10.3390/pharmaceutics14081566 |
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