Cargando…
Stabilisation of Viral Membrane Fusion Proteins in Prefusion Conformation by Structure-Based Design for Structure Determination and Vaccine Development
The membrane surface of enveloped viruses contains dedicated proteins enabling the fusion of the viral with the host cell membrane. Working with these proteins is almost always challenging because they are membrane-embedded and naturally metastable. Fortunately, based on a range of different example...
Autores principales: | Ebel, Henriette, Benecke, Tim, Vollmer, Benjamin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415420/ https://www.ncbi.nlm.nih.gov/pubmed/36016438 http://dx.doi.org/10.3390/v14081816 |
Ejemplares similares
-
Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion
por: Liu, Yuhang, et al.
Publicado: (2021) -
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
por: Hsieh, Ching-Lin, et al.
Publicado: (2022) -
The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane
por: Fontana, Juan, et al.
Publicado: (2017) -
Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation
por: Wrapp, Daniel, et al.
Publicado: (2020) -
Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
por: Yin, Hsien-Sheng, et al.
Publicado: (2006)