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Phosphate Metabolic Inhibition Contributes to Irradiation-Induced Myelosuppression through Dampening Hematopoietic Stem Cell Survival

Myelosuppression is a common and intractable side effect of cancer therapies including radiotherapy and chemotherapy, while the underlying mechanism remains incompletely understood. Here, using a mouse model of radiotherapy-induced myelosuppression, we show that inorganic phosphate (Pi) metabolism i...

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Detalles Bibliográficos
Autores principales:	Wu, Yiding, Liao, Weinian, Chen, Jun, Liu, Chaonan, Zhang, Shuzhen, Yu, Kuan, Wang, Xinmiao, Chen, Mo, Wang, Song, Ran, Xinze, Su, Yongping, Cheng, Tianmin, Wang, Junping, Du, Changhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415467/ https://www.ncbi.nlm.nih.gov/pubmed/36014901 http://dx.doi.org/10.3390/nu14163395

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