Glasdegib Dimaleate: Synthesis, Characterization and Comparison of Its Properties with Monomaleate Analogue

Glasdegib is a recently approved drug for the treatment of acute myeloid leukemia. It is formulated and marketed in monomaleate salt form. In our investigation, we were able to prepare a glasdegib dimaleate form, which could, in theory, exist in double-salt form or as a mixture of salt and co-crysta...

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Detalles Bibliográficos
Autores principales: Peklar, Boris, Perdih, Franc, Makuc, Damjan, Plavec, Janez, Cluzeau, Jérôme, Kitanovski, Zoran, Časar, Zdenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415664/
https://www.ncbi.nlm.nih.gov/pubmed/36015269
http://dx.doi.org/10.3390/pharmaceutics14081641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415664/
https://www.ncbi.nlm.nih.gov/pubmed/36015269
http://dx.doi.org/10.3390/pharmaceutics14081641

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