Impact of MnTBAP and Baricitinib Treatment on Hutchinson–Gilford Progeria Fibroblasts

Hutchinson–Gilford progeria syndrome (HGPS) is a rare premature aging disease. It is caused by a mutation in the LMNA gene, which results in a 50-amino-acid truncation of prelamin A. The resultant truncated prelamin A (progerin) lacks the cleavage site for the zinc-metallopeptidase ZMPSTE24. Progeri...

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Detalles Bibliográficos
Autores principales: Vehns, Elena, Arnold, Rouven, Djabali, Karima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415676/
https://www.ncbi.nlm.nih.gov/pubmed/36015093
http://dx.doi.org/10.3390/ph15080945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415676/
https://www.ncbi.nlm.nih.gov/pubmed/36015093
http://dx.doi.org/10.3390/ph15080945

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