Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice

Despite the intramuscular route being the most used vaccination strategy against SARS-CoV-2, the intradermal route has been studied around the globe as a strong candidate for immunization against SARS-CoV-2. Adjuvants have shown to be essential vaccine components that are capable of driving robust i...

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Detalles Bibliográficos
Autores principales: Firmino-Cruz, Luan, dos-Santos, Júlio Souza, da Fonseca-Martins, Alessandra Marcia, Oliveira-Maciel, Diogo, Guadagnini-Perez, Gustavo, Roncaglia-Pereira, Victor A., Dumard, Carlos H., Guedes-da-Silva, Francisca H., Vicente Santos, Ana C., Alvim, Renata G. F., Lima, Tulio M., Marsili, Federico F., Abreu, Daniel P. B., Rossi-Bergmann, Bartira, Vale, Andre M., Filardy, Alessandra D’Almeida, Silva, Jerson Lima, de Oliveira, Andrea Cheble, Gomes, Andre M. O., de Matos Guedes, Herbert Leonel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415730/
https://www.ncbi.nlm.nih.gov/pubmed/36016193
http://dx.doi.org/10.3390/vaccines10081305

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