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Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment

Octocrylene is an organic sunscreen whose main action is to absorb UVB radiation and short UVA wavelengths; it is used in various cosmetic products in order to provide an adequate sun-protection factor or to protect the cosmetic formulations themselves from UV radiation. This filter is believed to b...

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Autores principales: Medici, Antonio, Saviano, Lorenzo, Siciliano, Antonietta, Libralato, Giovanni, Guida, Marco, Previtera, Lucio, Di Fabio, Giovanni, Zarrelli, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415856/
https://www.ncbi.nlm.nih.gov/pubmed/36014525
http://dx.doi.org/10.3390/molecules27165286
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author Medici, Antonio
Saviano, Lorenzo
Siciliano, Antonietta
Libralato, Giovanni
Guida, Marco
Previtera, Lucio
Di Fabio, Giovanni
Zarrelli, Armando
author_facet Medici, Antonio
Saviano, Lorenzo
Siciliano, Antonietta
Libralato, Giovanni
Guida, Marco
Previtera, Lucio
Di Fabio, Giovanni
Zarrelli, Armando
author_sort Medici, Antonio
collection PubMed
description Octocrylene is an organic sunscreen whose main action is to absorb UVB radiation and short UVA wavelengths; it is used in various cosmetic products in order to provide an adequate sun-protection factor or to protect the cosmetic formulations themselves from UV radiation. This filter is believed to be a possible endocrine disruptor and is also questioned due to its allergic and/or photoallergic potential. However, it continues to be widely used, and it has been found in various environments, not least those of swimming pools, where it is evidently released by consumers, to the point that it is now considered an emerging micropollutant. The present investigation presents the possible chemical fate of octocrylene in the typical chlorination conditions of wastewater or swimming pools. A total of 11 disinfection byproducts were identified, and 6 were identified for the first time, and separated by HPLC. These products were identified through careful mass spectrometry studies and 1D and 2D NMR experiments. A formation mechanism has been proposed that justifies the chemical structures of all of the compounds identified. The ecotoxicological assessment of octocrylene and their products was carried out by employing Phaeodactylum tricornutum, Brachionus plicatilis and Aliivibrio fischeri as bioindicators. The ecotoxicity results reveal that toxic byproducts might be generated during the oxidation process, increasing the potential risk to the marine environment.
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spelling pubmed-94158562022-08-27 Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment Medici, Antonio Saviano, Lorenzo Siciliano, Antonietta Libralato, Giovanni Guida, Marco Previtera, Lucio Di Fabio, Giovanni Zarrelli, Armando Molecules Article Octocrylene is an organic sunscreen whose main action is to absorb UVB radiation and short UVA wavelengths; it is used in various cosmetic products in order to provide an adequate sun-protection factor or to protect the cosmetic formulations themselves from UV radiation. This filter is believed to be a possible endocrine disruptor and is also questioned due to its allergic and/or photoallergic potential. However, it continues to be widely used, and it has been found in various environments, not least those of swimming pools, where it is evidently released by consumers, to the point that it is now considered an emerging micropollutant. The present investigation presents the possible chemical fate of octocrylene in the typical chlorination conditions of wastewater or swimming pools. A total of 11 disinfection byproducts were identified, and 6 were identified for the first time, and separated by HPLC. These products were identified through careful mass spectrometry studies and 1D and 2D NMR experiments. A formation mechanism has been proposed that justifies the chemical structures of all of the compounds identified. The ecotoxicological assessment of octocrylene and their products was carried out by employing Phaeodactylum tricornutum, Brachionus plicatilis and Aliivibrio fischeri as bioindicators. The ecotoxicity results reveal that toxic byproducts might be generated during the oxidation process, increasing the potential risk to the marine environment. MDPI 2022-08-19 /pmc/articles/PMC9415856/ /pubmed/36014525 http://dx.doi.org/10.3390/molecules27165286 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Medici, Antonio
Saviano, Lorenzo
Siciliano, Antonietta
Libralato, Giovanni
Guida, Marco
Previtera, Lucio
Di Fabio, Giovanni
Zarrelli, Armando
Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment
title Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment
title_full Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment
title_fullStr Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment
title_full_unstemmed Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment
title_short Octocrylene: From Sunscreens to the Degradation Pathway during Chlorination Processes: Formation of Byproducts and Their Ecotoxicity Assessment
title_sort octocrylene: from sunscreens to the degradation pathway during chlorination processes: formation of byproducts and their ecotoxicity assessment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415856/
https://www.ncbi.nlm.nih.gov/pubmed/36014525
http://dx.doi.org/10.3390/molecules27165286
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