Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp(2))-H-Hydroxylation

The continuous, worldwide spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) endanger the World Health Organization’s (WHO) goal to end the global TB pandemic by the year 2035. During the past 50 years, very few new drugs have been approved by medical agencies...

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Detalles Bibliográficos
Autores principales: Berger, Alexander, Knak, Talea, Kiffe-Delf, Anna-Lene, Mudrovcic, Korana, Singh, Vinayak, Njoroge, Mathew, Burckhardt, Bjoern B., Gopalswamy, Mohanraj, Lungerich, Beate, Ackermann, Lutz, Gohlke, Holger, Chibale, Kelly, Kalscheuer, Rainer, Kurz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415896/
https://www.ncbi.nlm.nih.gov/pubmed/36015133
http://dx.doi.org/10.3390/ph15080984

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