Design, Synthesis, and Development of Pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part II—Benzimidazole Derivatives

Phosphoinositide 3-kinase (PI3K) is the family of lipid kinases participating in vital cellular processes such as cell proliferation, growth, migration, or cytokines production. Due to the high expression of these proteins in many human cells and their involvement in metabolism regulation, normal em...

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Detalles Bibliográficos
Autores principales: Stypik, Mariola, Michałek, Stanisław, Orłowska, Nina, Zagozda, Marcin, Dziachan, Maciej, Banach, Martyna, Turowski, Paweł, Gunerka, Paweł, Zdżalik-Bielecka, Daria, Stańczak, Aleksandra, Kędzierska, Urszula, Mulewski, Krzysztof, Smuga, Damian, Maruszak, Wioleta, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Pietruś, Wojciech, Ochal, Zbigniew, Mach, Mateusz, Zygmunt, Beata, Pieczykolan, Jerzy, Dubiel, Krzysztof, Wieczorek, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415947/
https://www.ncbi.nlm.nih.gov/pubmed/36015075
http://dx.doi.org/10.3390/ph15080927

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