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Spray-Dried Cytisine-Loaded Matrices: Development of Transbuccal Sustained-Release Tablets as a Promising Tool in Smoking Cessation Therapy
Cytisine (CYT) has emerged as a promising molecule to treat nicotine addiction, since it acts as a partial agonist of nicotinic acetylcholine receptors. However, its unfavorable pharmacokinetic properties lead to multiple administrations per day, reducing the patient’s compliance and increasing the...
Autores principales: | Angellotti, Giuseppe, Di Prima, Giulia, Scarpaci, Amalia Giulia, D’Agostino, Fabio, Campisi, Giuseppina, De Caro, Viviana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416034/ https://www.ncbi.nlm.nih.gov/pubmed/36015209 http://dx.doi.org/10.3390/pharmaceutics14081583 |
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