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Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature

We report a case of cervical blastomycosis with associated paravertebral involvement and severe spinal canal stenosis in a 48-year-old patient presenting with acute airway obstruction from a retropharyngeal abscess. Our case was also complicated by severe hypokalemia that developed during the blasto...

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Autores principales: Hanna, John J, Guastadisegni, Jessica M, Kouma, Marcus A, Knez, Emily B, Arasaratnam, Reuben J, Storey, Donald F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416057/
https://www.ncbi.nlm.nih.gov/pubmed/36043181
http://dx.doi.org/10.1093/ofid/ofac414
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author Hanna, John J
Guastadisegni, Jessica M
Kouma, Marcus A
Knez, Emily B
Arasaratnam, Reuben J
Storey, Donald F
author_facet Hanna, John J
Guastadisegni, Jessica M
Kouma, Marcus A
Knez, Emily B
Arasaratnam, Reuben J
Storey, Donald F
author_sort Hanna, John J
collection PubMed
description We report a case of cervical blastomycosis with associated paravertebral involvement and severe spinal canal stenosis in a 48-year-old patient presenting with acute airway obstruction from a retropharyngeal abscess. Our case was also complicated by severe hypokalemia that developed during the blastomycosis treatment course with posaconazole and which improved after discontinuation and replacement therapy. After 12 months of blastomycosis-targeted therapy, our patient had complete resolution of clinical, laboratory, and radiological findings of blastomycosis.
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spelling pubmed-94160572022-08-29 Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature Hanna, John J Guastadisegni, Jessica M Kouma, Marcus A Knez, Emily B Arasaratnam, Reuben J Storey, Donald F Open Forum Infect Dis Id Teaching Cases We report a case of cervical blastomycosis with associated paravertebral involvement and severe spinal canal stenosis in a 48-year-old patient presenting with acute airway obstruction from a retropharyngeal abscess. Our case was also complicated by severe hypokalemia that developed during the blastomycosis treatment course with posaconazole and which improved after discontinuation and replacement therapy. After 12 months of blastomycosis-targeted therapy, our patient had complete resolution of clinical, laboratory, and radiological findings of blastomycosis. Oxford University Press 2022-08-11 /pmc/articles/PMC9416057/ /pubmed/36043181 http://dx.doi.org/10.1093/ofid/ofac414 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Id Teaching Cases
Hanna, John J
Guastadisegni, Jessica M
Kouma, Marcus A
Knez, Emily B
Arasaratnam, Reuben J
Storey, Donald F
Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature
title Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature
title_full Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature
title_fullStr Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature
title_full_unstemmed Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature
title_short Blastomycosis Presenting With Acute Airway Obstruction From a Retropharyngeal Abscess and Complicated by Severe Hypokalemia During Posaconazole Therapy: A Case Report and Review of Literature
title_sort blastomycosis presenting with acute airway obstruction from a retropharyngeal abscess and complicated by severe hypokalemia during posaconazole therapy: a case report and review of literature
topic Id Teaching Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416057/
https://www.ncbi.nlm.nih.gov/pubmed/36043181
http://dx.doi.org/10.1093/ofid/ofac414
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