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Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity

Due to an escalating increase in multiple antibiotic resistance among bacteria, novel nanomaterials with antimicrobial properties are being developed to prevent infectious diseases caused by bacteria that are common in wastewater and the environment. A series of nanolayered structures and nanohybrid...

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Autores principales: Alali, Hasna Abdullah, Saber, Osama, Berekaa, Mahmoud Mohamed, Osama, Doaa, Ezzeldin, Mohamed Farouk, Shaalan, Nagih M., AlMulla, Abdulaziz Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416148/
https://www.ncbi.nlm.nih.gov/pubmed/36014614
http://dx.doi.org/10.3390/nano12162749
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author Alali, Hasna Abdullah
Saber, Osama
Berekaa, Mahmoud Mohamed
Osama, Doaa
Ezzeldin, Mohamed Farouk
Shaalan, Nagih M.
AlMulla, Abdulaziz Abdulrahman
author_facet Alali, Hasna Abdullah
Saber, Osama
Berekaa, Mahmoud Mohamed
Osama, Doaa
Ezzeldin, Mohamed Farouk
Shaalan, Nagih M.
AlMulla, Abdulaziz Abdulrahman
author_sort Alali, Hasna Abdullah
collection PubMed
description Due to an escalating increase in multiple antibiotic resistance among bacteria, novel nanomaterials with antimicrobial properties are being developed to prevent infectious diseases caused by bacteria that are common in wastewater and the environment. A series of nanolayered structures and nanohybrids were prepared and modified by several methods including an ultrasonic technique, intercalation reactions of fatty acids, and carbon nanotubes, in addition to creating new phases based on zinc and aluminum. The nanomaterials prepared were used against a group of microorganisms, including E. coli, S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. Experimental results revealed that a nanohybrid based on carbon nanotubes and fatty acids showed significant antimicrobial activity against E. coli, and can be implemented in wastewater treatment. Similar behavior was observed for a nanolayered structure which was prepared using ultrasonic waves. For the other microorganisms, a nanolayered structure combined with carbon nanotubes showed a significant and clear inhibitory effect on S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. It is concluded that the nanolayered structures and nanohybrids, which can be modified at low cost with high productivity, using simple operations and straightforward to use equipment, can be considered good candidates for preventing infectious disease and inhibiting the spread of bacteria, especially those that are commonly found in wastewater and the environment.
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spelling pubmed-94161482022-08-27 Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity Alali, Hasna Abdullah Saber, Osama Berekaa, Mahmoud Mohamed Osama, Doaa Ezzeldin, Mohamed Farouk Shaalan, Nagih M. AlMulla, Abdulaziz Abdulrahman Nanomaterials (Basel) Article Due to an escalating increase in multiple antibiotic resistance among bacteria, novel nanomaterials with antimicrobial properties are being developed to prevent infectious diseases caused by bacteria that are common in wastewater and the environment. A series of nanolayered structures and nanohybrids were prepared and modified by several methods including an ultrasonic technique, intercalation reactions of fatty acids, and carbon nanotubes, in addition to creating new phases based on zinc and aluminum. The nanomaterials prepared were used against a group of microorganisms, including E. coli, S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. Experimental results revealed that a nanohybrid based on carbon nanotubes and fatty acids showed significant antimicrobial activity against E. coli, and can be implemented in wastewater treatment. Similar behavior was observed for a nanolayered structure which was prepared using ultrasonic waves. For the other microorganisms, a nanolayered structure combined with carbon nanotubes showed a significant and clear inhibitory effect on S. aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. It is concluded that the nanolayered structures and nanohybrids, which can be modified at low cost with high productivity, using simple operations and straightforward to use equipment, can be considered good candidates for preventing infectious disease and inhibiting the spread of bacteria, especially those that are commonly found in wastewater and the environment. MDPI 2022-08-11 /pmc/articles/PMC9416148/ /pubmed/36014614 http://dx.doi.org/10.3390/nano12162749 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alali, Hasna Abdullah
Saber, Osama
Berekaa, Mahmoud Mohamed
Osama, Doaa
Ezzeldin, Mohamed Farouk
Shaalan, Nagih M.
AlMulla, Abdulaziz Abdulrahman
Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity
title Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity
title_full Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity
title_fullStr Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity
title_full_unstemmed Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity
title_short Impact of Nanolayered Material and Nanohybrid Modifications on Their Potential Antibacterial Activity
title_sort impact of nanolayered material and nanohybrid modifications on their potential antibacterial activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416148/
https://www.ncbi.nlm.nih.gov/pubmed/36014614
http://dx.doi.org/10.3390/nano12162749
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